| Tm | Name | W | L | Start | End | |
|---|---|---|---|---|---|---|
| BOS | Lou Boudreau | 76 | 78 | Beg | End | |
| BOS | Tommy Holmes | 13 | 22 | Beg | 19520530 | |
| BOS | Charlie Grimm | 51 | 67 | 19520601 | End | |
| CHA | Paul Richards | 81 | 73 | Beg | End | |
| CHN | Phil Cavarretta | 77 | 77 | Beg | End | |
| CIN | Luke Sewell | 39 | 59 | Beg | 19520729 | |
| CIN | Earle Brucker | 3 | 2 | 19520730 | 19520803 | |
| CIN | Rogers Hornsby | 27 | 24 | 19520805 | End | |
| CLE | Al Lopez | 93 | 61 | Beg | End | |
| DET | Red Rolfe | 23 | 49 | Beg | 19520704 | |
| DET | Fred Hutchinson | 27 | 55 | 19520705 | End | |
| LAN | Chuck Dressen | 96 | 57 | Beg | End | |
| NYA | Casey Stengel | 95 | 59 | Beg | End | |
| OAK | Jimmy Dykes | 79 | 75 | Beg | End | |
| PHI | Eddie Sawyer | 28 | 35 | Beg | 19520627 | |
| PHI | Steve O'Neill | 59 | 32 | 19520628 | End | |
| PIT | Billy Meyer | 42 | 112 | Beg | End | |
| SFN | Leo Durocher | 92 | 62 | Beg | End | |
| SLN | Rogers Hornsby | 22 | 29 | Beg | 19520608 | |
| SLN | Eddie Stanky | 88 | 66 | Beg | End | |
| SLN | Marty Marion | 42 | 61 | 19520610 | End | |
| TEX | Bucky Harris | 78 | 76 | Beg | End |
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